Allergen Profile With Total IgE, Respiratory−Area 10

Casandra

Casandra Test Code LC00416Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 602640CPT Codes 82785, 86003

Allergen Profile With Total IgE, Respiratory−Area 10

Clinical Use

Use

Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.

Special Instructions

This test covers allergens specific to the Oklahoma and Texas regions. It includes a wide range of allergens, such as grasses, trees, molds, and dander. Serum collected should be stored at room temperature, and causes for rejection include inadequate labeling and gross hemolysis.

Limitations

The test's ability to detect allergen-specific IgE is dependent on the presence of relevant antibodies in the serum. It may not detect all forms of allergic reactions, especially non-IgE mediated hypersensitivities. False negatives or positives can occur if the component allergen antibodies are below detectable levels or due to interference from other immunological factors. The test may not fully represent inhalant allergens from regions outside the listed areas, and cross-reactivity may affect allergen specificity.

Test Details