Allergen Profile With Total IgE, Respiratory−Area 15
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
The test can be used when evaluating individuals taking medications, such as long-acting antihistamines, that may interfere with other testing modalities like skin testing. It is also applicable when immunotherapy based on skin testing results hasn't led to satisfactory symptom remission or when individuals show unresponsiveness to medical management, making identification of specific allergens beneficial.
Limitations
The test is specific to the allergens prevalent in the designated geographic area (Area 15) and may not detect allergic responses to substances not included in the panel. Additionally, results should be interpreted in the context of clinical symptoms and history, as false positives and negatives can occur. Other confirmatory tests may be required for comprehensive diagnosis.
Methodology
Immunoassay (Thermo Fisher ImmunoCAP®)
Biomarkers
LOINC Codes
- 8251-1
- 19113-0
- 6096-2
- 6095-4
- 6833-8
- 6098-8
- 6041-8
- 6265-3
- 6078-0
- 6212-5
- 6075-6
- 6025-1
- 6020-2
- 7155-5
- 6178-8
- 6189-5
- 6109-3
- 6192-9
- 6090-5
- 6281-0
- 6085-5
- 6183-8
- 6234-9
- 7604-2
- 6181-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 18 months |
