Allergen Profile With Total IgE, Respiratory–Area 20
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. Additional time should be allowed for confirmatory or reflex tests, especially if schedules vary.
Limitations
The test may be limited by factors including the potential for interference by medications such as long-acting antihistamines, which generally affect skin testing results rather than blood-based assays like this IgE test. Additionally, results may vary based on biological variability in IgE production or different environmental exposures. Elevated IgE levels can indicate many different allergens, and as such, specific sensitivity to a particular allergen should be corroborated with clinical correlation.
Methodology
Immunoassay (Thermo Fisher ImmunoCAP®)
Biomarkers
LOINC Codes
- 8251-1
- 19113-0
- 6020-2
- 6025-1
- 6034-3
- 7124-1
- 6041-8
- 6833-8
- 6077-2
- 6078-0
- 6085-5
- 6096-2
- 6095-4
- 6098-8
- 6110-1
- 6113-5
- 6075-6
- 6173-9
- 6179-6
- 6182-0
- 6222-4
- 6212-5
- 7369-2
- 7604-2
- 6282-8
- 6286-9
- 6281-0
- 6181-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
