Allergen Profile With Total IgE, Respiratory−Area 6
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
Test assesses IgE levels specific to a comprehensive set of allergens found in Alabama, Arkansas, Louisiana, and Mississippi. Proper specimen handling and labeling are critical to avoid rejection. Ensure adequate sample volume and container use based on described requirements.
Limitations
The test evaluates IgE responses to multiple allergens but does not substitute for detailed clinical evaluation. Results can vary with medication interference; therefore, medications should be checked for interference potential. False negatives can occur with low IgE responses or recent allergen exposure. Additional confirmatory tests may be necessary when results are borderline or in complex clinical scenarios.
Methodology
Immunoassay (Thermo Fisher ImmunoCAP®)
Biomarkers
LOINC Codes
- 8251-1
- 19113-0
- 6096-2
- 6095-4
- 6833-8
- 6098-8
- 6041-8
- 6265-3
- 6078-0
- 6212-5
- 6075-6
- 6025-1
- 6020-2
- 7155-5
- 15283-5
- 6178-8
- 6189-5
- 6109-3
- 33982-0
- 6209-1
- 6281-0
- 6085-5
- 7604-2
- 6232-3
- 6181-2
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 18 months |
