Anaplasma phagocytophilum (HGE) Antibody, IgG and IgM, IFA
Also known as: Anaplasma phagocytophilum, Ehrlichia, HGE, Tickborne
Use
This test is used for detection and semiquantitation of serum IgG and IgM antibodies to Anaplasma phagocytophilum (HGE) to aid in the diagnosis of human granulocytic ehrlichiosis.
Special Instructions
Antibiotic therapy should not be delayed for patients suspected of ehrlichiosis. The presence of antibodies alone cannot confirm acute infection; DNA PCR is preferred for acute diagnosis. IgM antibodies are less specific and may lead to false positives.
Limitations
The diagnosis of acute anaplasmosis cannot be confirmed solely by presence of Anaplasma antibody in a serum sample collected at a single time point. Antibody titers are frequently negative during the first 7-10 days of illness. IgM results should not be solely used for diagnosis due to higher likelihood of false positive results.
Methodology
Immunoassay (Indirect fluorescent antibody (IFA))
Biomarkers
LOINC Codes
- 55150-7
- 23877-4
- 23878-2
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.4 mL
Minimum Volume
0.2 mL
Container
Red-top tube or gel-barrier tube or serum transfer tube
Collection Instructions
Specimen should be free of bacterial contamination, hemolysis, and lipemia.
Storage Instructions
Refrigerate.
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination