Apolipoprotein B
Also known as: Beta Apolipoprotein
Use
LDL and its major protein, apolipoprotein B, play an essential role in lipid transport and metabolism. Apo B may regulate cholesterol synthesis through its interaction with specific cell membrane receptors and by inhibition of HMG Co A reductase. This enzyme has been identified as the rate controlling enzyme in cholesterol biosynthesis. Apo B may be important in the genesis of atherosclerosis and its quantitation useful in the evaluation of patients at risk for or having coronary atherosclerosis (CAD). High levels indicate increased risk for CAD.
Special Instructions
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Limitations
The test is intended for the evaluation of patients at risk for or having coronary atherosclerosis (CAD). However, this test alone does not diagnose CAD or any specific medical condition. It should be interpreted in conjunction with other clinical and laboratory data. The result of Apolipoprotein B testing may be influenced by acute illnesses, nutritional status, and certain medications.
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 1884-6
- 1884-6
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
Not provided
Container
Red-top tube, gel-barrier tube
Collection Instructions
Separate serum or plasma from cells. Transfer specimen to a plastic transport tube.
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |