Bacterial Vaginosis (Sialidase), Trichomonas vaginalis, NAA, Vaginal Yeast Culture
Also known as: BV (Sialidase), Tv (NAA), Vaginal Yeast (Culture)
Use
BV (sialidase) activity: Enzyme activity test for use in the detection of vaginal fluid specimens for sialidase activity, an enzyme produced by bacteria associated with bacterial vaginitis, including Bacteroides spp, Prevotella spp, and Mobiluncus spp, and some G vaginalis. In a recent study, Bradshaw et al demonstrated the test to be 88% sensitive and 95% specific.
Special Instructions
Specimen collection should avoid the cervix to prevent increased risk to OB patients and potential false results, as cervical sialidase activity may differ. Avoid collecting from patients who have used vaginal creams, ointments, spermicides, or douches within 72 hours as results could be affected. Ensure correct specimen labeling to avoid rejection.
Limitations
The test may yield false-negative results if the specimen is collected incorrectly, insufficiently, or from patients currently undergoing antimicrobial therapy. Collection from the cervix, after use of vaginal creams or douches, or from unsuitable swabs or transport methods can lead to inaccurate findings. Specimens from children under the age of 13 may require additional handling.
Methodology
Other
Biomarkers
LOINC Codes
- 41477-1
- 18483-8
- 46154-1
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Not provided
Minimum Volume
Not provided
Container
Copan double swab in Aimes liquid medium and Aptima® unisex swab transport
Collection Instructions
Using transport swabs provided, collect vaginal fluid sample by contacting the lower one-third of the vaginal wall, rotating for 10 to 20 seconds to absorb fluid. Immediately place the swabs into the transport tubes. For the Aptima® swab, carefully break the swab shaft against the side of the tube. Tightly screw on the cap.
Storage Instructions
Maintain specimen at room temperature or refrigerate (2°C to 30°C).
Causes for Rejection
Specimen collected or transport other than previously described; unlabeled specimens or those with a discrepancy between the specimen label and the request form; Aptima® Combo 2 (AC2) swab specimen transport tube with two swabs or swab not supplied by Gen-Probe® or no swab; UTM transport from an inappropriate site; vaginal swab devices from patients younger than 16 years of age; ProbeTec™ swabs.