Bile Acids
Also known as: Glyco and Taurochenodeoxycholic Acid
Use
Evaluate the enterohepatic cycle consisting of the biliary system, intestine, portal circulation, and hepatocytes
Special Instructions
Patient should be fasting; however, a two-hour postprandial level has been used in order to evaluate hepatic function after the gallbladder has been completely emptied. For women with intrahepatic cholestasis of pregnancy who need peak bile acid testing, samples may be taken postprandially. To avoid delays, submit separate frozen specimens for each test requested.
Limitations
Specimens from patients who are on Ursodeoxycholic Acid (UDCA) treatment are not suitable for use with this assay. Instead, use Bile Acids, Fractionated and Total, LC/MS-MS [503640]. In the absence of bile acid tests, elevated ALT, AST, and/or alkaline phosphatase levels with intense pruritus may diagnose cholestasis of pregnancy.
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 14628-2
- 14628-2
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube
Collection Instructions
Transfer serum or plasma to a plastic transport tube before freezing.
Patient Preparation
Patient should be fasting; samples may be taken postprandially for specific conditions.
Storage Instructions
Freeze.
Causes for Rejection
Transported or received at room temperature. Specimens from patients on Ursodeoxycholic Acid (UDCA) treatment.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 3 days |
| Frozen | 7 days |