Calcitonin (Thyrocalcitonin), Two Specimens
Use
The Calcitonin (Thyrocalcitonin) test is used primarily for evaluating patients suspected of having medullary thyroid carcinoma (MTC), a form of thyroid cancer. The test is performed using two specimens collected at different time points. An initial baseline sample is taken, followed by treatment with a stimulatory agent or medication, and a subsequent sample is taken to measure the stimulated levels of calcitonin. Elevated calcitonin levels, particularly after stimulation, may indicate MTC or other conditions such as C-cell hyperplasia.
Special Instructions
The test requires multiple specimens to be taken at designated time points. The first specimen serves as a baseline. After administering a stimulant, such as a medication or agent, additional specimens are collected. It is important not to collect this series before confirming the proper protocol with the ordering clinician. Incorrect time points or failure to administer the appropriate stimulant can affect the reliability of the test.
Limitations
The Calcitonin test results should not be used interchangeably with those obtained through other assay methods or kits. Variability in assay methods can lead to differences in results, affecting interpretation. Furthermore, certain medications or physical conditions might influence the level of calcitonin in the blood, potentially leading to false positives or negatives. The use of this test as a monitoring tool for MTC and other conditions should be guided by clinical practice guidelines and physician discretion.
Methodology
Immunoassay (ICMA)
Biomarkers
LOINC Codes
- 33788-1
- 46963-5
- 58892-1
- 58892-1
- 33788-1
- 46963-5
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided