Carbohydrate-deficient Transferrin (CDT), Adult
Also known as: Diasialotransferrin, Transferrin Isoforms
Use
An indicator of chronic alcohol abuse
Special Instructions
Not provided.
Limitations
The CDT test is not appropriate for evaluating congenital disorders of glycosylation (CDG syndrome), genetic variants of transferrin, monoclonal components, or cases involving high polyclonal increases. It is also not suitable for assessing liver injuries (such as cirrhosis due to chronic alcohol abuse or end-stage liver disease). Furthermore, the test results are not specific for medico-legal purposes.
Methodology
Other
Biomarkers
Carbohydrate-deficient transferrin
Analyte
LOINC Codes
- 48495-6 - CDT/Tf MFr SerPl
- 48495-6 - CDT/Tf MFr SerPl
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.75 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Serum should be separated from cells within two hours of venipuncture. Send serum frozen in a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze.
Causes for Rejection
Fibrinogen present in sample; hemolyzed specimen; aged and improperly stored specimen; anticoagulated specimen (citrate, EDTA); presence of genetic variants of transferrin
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 days |
| Refrigerated | 2 days |
| Frozen | 7 days |
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