Chlamydia/Gonococcus − Client-provided Aliquot
Use
The test is designed to detect Chlamydia trachomatis and/or Neisseria gonorrhoeae. These are common sexually transmitted infections that can have serious health consequences if left untreated. Early and accurate detection is critical to prevent complications such as infertility, pelvic inflammatory disease, ectopic pregnancy, and chronic pelvic pain.
Special Instructions
Specimens must be handled with precautions to prevent cross-contamination. The PreservCyt® fluid is used, and it must be transferred to the Aptima® specimen transport tube. Training for preventing cross-contamination should be provided by Hologic.
Limitations
There is no evidence of cytology results degradation by aliquot removal; however, this cannot be ruled out for all specimens. Misallocation of diagnostic cells could occur if they are extremely rare. Aliquot removal may not leave sufficient material for ThinPrep® Pap Test™ slide preparation. It may also impact the performance of ancillary testing like reflexive HPV testing. Separate sample collection for ThinPrep® Pap Test™ and STD testing may be considered.
Methodology
PCR-based (Nucleic acid amplification (NAA))
Biomarkers
LOINC Codes
- 45068-4
- 50387-0
- 50388-8
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
1 mL
Minimum Volume
1 mL
Container
Gen-Probe® Aptima® swab transport or Gen-Probe® Aptima® specimen transfer kit with 1 mL of PreservCyt® fluid
Collection Instructions
ThinPrep® preservative vial processing instructions should be followed, ensuring to avoid contamination. The aliquot removal should be performed outside amplification areas.
Storage Instructions
Store the aliquot in Aptima® tube at 15°C to 30°C. Aliquots must be transferred within seven days of collection.
Causes for Rejection
Rejection occurs if received in Gen-Probe Pace® transport system, bacterial swab specimen, with multiple swabs, in grossly leaking transport container, with fixative or additives, in expired transport media, or in incorrect transport device, or after prolonged delay in transport (usually more than 72 hours), with swab in transport device, unlabeled specimen, or name discrepancy between specimen and request label, with more than 1 mL of PreservCyt® added