Chromium and Cobalt, Whole Blood
Use
Detect metal ion accumulation caused by metal-on-metal (MoM) implants.
Special Instructions
The test results are used as an adjunct in the clinical assessment of patients with MoM implants. Metal ion levels alone should not determine clinical recommendations for revision surgery. Storage instructions indicate room temperature for submission/transport within three days, and refrigerated or frozen storage is advised for periods exceeding this duration.
Limitations
The reference interval and risk stratification are specific to patients with metal-on-metal orthopedic implants. The test does not combine chromium and cobalt levels for risk stratification but evaluates them individually. Metal ion tests provide adjunctive information for clinical evaluation but should not solely guide clinical decisions regarding revision surgery. Additional confirmatory or reflex tests may require extended turnaround time.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 5619-2
- 5625-9
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
0.5 mL
Container
Royal blue-top (EDTA) metal-free tube
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.