Chromosome Analysis, High Resolution
Also known as: High Resolution G-Banding, Prophase Analysis
Use
Detect small chromosome abnormalities not detectable using routine methods; precise identification of abnormal chromosomes previously detected by routine methods
Special Instructions
Pertinent medical findings must accompany the request for chromosome analysis. For specimens such as cord blood or fetal blood, Test No. 510180 will be added to exclude maternal origin. It is crucial to handle specimens properly, as improper anticoagulants or frozen specimens cannot be processed.
Limitations
This test may not detect subtler chromosomal rearrangements that are below the resolution limit of cytogenetic analysis. Additionally, it may not identify congenital anomalies caused by other etiologies. As such, genetic counseling is recommended for comprehensive assessment and consideration of potential preimplantation genetic diagnosis in relevant cases.
Methodology
Chromosomal / Cytogenetics
Biomarkers
LOINC Codes
- 62361-1
- 55199-4
- 62360-3
- 62358-7
- 48818-9
- 50619-6
- 31208-2
- 48672-0
Result Turnaround Time
10-15 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL (adults), 2 mL (neonates)
Minimum Volume
2 mL
Container
Green-top (sodium heparin) tube
Collection Instructions
Using sterile technique, collect 5 mL of blood into a green-top (sodium heparin) tube or syringe. Invert the tube several times to prevent coagulation. Specimens should be sent the same day as collected.
Storage Instructions
Specimen should be delivered immediately. Maintain specimen at room temperature. Specimen may be refrigerated if there is a delay in shipment. Do not freeze.
Causes for Rejection
Suitability of specimen will be determined by the Cytogenetics laboratory upon receipt. Improper anticoagulant and frozen specimens cannot be processed.