Chromosome Analysis, Solid Tumor
Use
Detection of chromosomal abnormalities with subgroup-specific diagnostic and prognostic significance (eg, t(11;22) in Ewing sarcoma)
Special Instructions
Fluorescence in situ Hybridization (FISH), Oncology [510669] is preferred for FNAs/core biopsies; specimen types and tumor details should be indicated on the test request form. Contact oncology customer service at 800-345-4363 for any inquiries regarding the test.
Limitations
The test has not been cleared or approved by the FDA. Chromosomal analysis may not detect all chromosomal abnormalities and does not rule out the presence of neoplasia. The effectiveness of the analysis can vary based on tumor type due to potential contamination with normal stroma or lack of viable tumor cells.
Methodology
Chromosomal / Cytogenetics (Karyotype)
Biomarkers
LOINC Codes
- 62389-2
- 31208-2
- 62361-1
- 62360-3
- 55199-4
- 62358-7
- 62356-1
- 62365-2
- 48672-0
- 11502-2
Result Turnaround Time
10-14 days
Related Documents
For more information, please review the documents below
Specimen
Tumor Tissue (Fresh)
Volume
0.5 to 1 cm3 tissue
Minimum Volume
Not provided
Container
Lymph node transport bottle or sterile tube containing Ringer's lactate
Collection Instructions
Submit at room temperature using Lymph Node Transport Kit provided by Labcorp. Specimens should reach the laboratory within 48 hours of collection. Indicate collection date and time on the test request form.
Storage Instructions
Maintain specimen at room temperature; refrigerate if sterility is questionable.
Causes for Rejection
Suitability of specimen will be determined by the Cytogenetics laboratory. Gross contamination, frozen, or fixed specimens cannot be processed.