Chromosome Five-cell Count Plus Microarray (Reveal®), Whole Blood
Also known as: Abbreviated Blood Chromosome Analysis, Microarray, Blood (Reveal®), SNP
Use
This test will detect chromosomal imbalances that could be associated with developmental delay/congenital anomalies. It provides detection of possible uniparental disomy of any chromosome, the percent and location of homozygosity, including the degree of identity by descent.
Special Instructions
The test includes two analyses and one karyotype, with a complete Chromosome SNP Microarray Questionnaire recommended upon specimen submission. There is no charge for follow-up parental testing if a child is found with an abnormal array of unknown clinical significance that may be clarified through parental testing.
Limitations
The SNP assay does not detect balanced rearrangements, low-level mosaicism (<10%), marker chromosomes containing only heterochromatin, or tetraploidy. It was developed and performance characteristics determined by Labcorp, without FDA clearance or approval.
Methodology
Microarray
Biomarkers
LOINC Codes
- 62361-1
- 55199-4
- 62360-3
- 62358-7
- 62365-2
- 50619-6
- 31208-2
- 48672-0
- 62378-5
- 62376-9
- 62357-9
- 62361-1
- 55199-4
- 62360-3
- 62358-7
- 62365-2
- 50619-6
- 31208-2
- 48672-0
- 11502-2
Result Turnaround Time
14-17 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL (adults), 2 mL (neonates)
Minimum Volume
2 mL (neonatal)
Container
Green-top (sodium heparin) tube (preferred) or yellow-top (ACD) tube is acceptable
Collection Instructions
Using sterile technique, collect 5 mL of blood into a green-top (sodium heparin) tube or syringe. Invert the tube to prevent coagulation. Send specimens the same day as collected. Improper anticoagulant fixed specimens and/or frozen specimens cannot be processed.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Suitability of specimen determined by the Cytogenetics laboratory.