Chromosome Five-cell Count Plus Microarray (Reveal®), Whole Blood

Casandra

Casandra Test Code LC74265Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 511535CPT Codes 81229, 88230, 88261

Chromosome Five-cell Count Plus Microarray (Reveal®), Whole Blood

Also known as: Abbreviated Blood Chromosome Analysis, Microarray, Blood (Reveal®), SNP

Clinical Use

Order Test

Use

This test will detect chromosomal imbalances that could be associated with developmental delay/congenital anomalies. It provides detection of possible uniparental disomy of any chromosome, the percent and location of homozygosity, including the degree of identity by descent.

Special Instructions

Not provided.

Limitations

The SNP assay does not detect balanced rearrangements, low-level mosaicism (<10%), marker chromosomes containing only heterochromatin, or tetraploidy. It was developed and performance characteristics determined by Labcorp, without FDA clearance or approval.

Test Details

Methodology

Microarray

Biomarkers

SNP Microarray Analysis

LOINC Codes

Order Codes

62361-1 - Cells counted
55199-4 - Cells karyotyped.total Bld/T
62360-3 - Cells analyzed
62358-7 - ISCN band level Ql
62365-2 - Diagnostic imp Spec-Imp
50619-6 - Karyotyp Bld/T
31208-2 - Specimen source
48672-0 - Clinical cytogeneticist Spec
62378-5 - Chrom copy # change
62376-9 - Microarray platform version
62357-9 - Chrom analy overall interp-Imp

Result Codes

62361-1 - Cells counted
55199-4 - Cells karyotyped.total Bld/T
62360-3 - Cells analyzed
62358-7 - ISCN band level Ql
62365-2 - Diagnostic imp Spec-Imp
50619-6 - Karyotyp Bld/T
31208-2 - Specimen source
48672-0 - Clinical cytogeneticist Spec
11502-2 - Laboratory report

Result Turnaround Time

14-17 days

Specimen

Whole Blood

Volume

5 mL (adults), 2 mL (neonates)

Minimum Volume

2 mL (neonatal)

Container

Green-top (sodium heparin) tube (preferred) or yellow-top (ACD) tube is acceptable

Collection Instructions

Using sterile technique, collect 5 mL of blood into a green-top (sodium heparin) tube or syringe. Invert the tube to prevent coagulation. Send specimens the same day as collected. Improper anticoagulant fixed specimens and/or frozen specimens cannot be processed.