Common Variable Immunodeficiency Syndrome (CVID): TNFRSF13B (TACI) (Full Gene Sequencing)
Use
Confirm a clinical diagnosis of TACI; allow early diagnosis in family members, guiding prophylactic measures
Special Instructions
Not provided.
Limitations
The methodology does not reliably detect mosaic variants, large deletions, large duplications, inversions, or other rearrangements, and may be affected by allele-dropout. It may not accurately determine the exact number of T/A or microsatellite repeats, and cannot conclude whether two heterozygous variants are on the same or different chromosome copies. The test was developed and its performance characteristics were determined by Labcorp and is not cleared or approved by the FDA.
Methodology
NGS (Targeted)
Biomarkers
TNFRSF13B
Gene
LOINC Codes
- 57758-5 - TNFRSF13B gene Mut Anl Bld/T
- 57758-5 - TNFRSF13B gene Mut Anl Bld/T
Result Turnaround Time
21-35 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
2 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tube
Collection Instructions
Samples may be stored for brief periods at 4°C. Ship overnight at room temperature.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Container broken or leaking; container not labeled or label not legible; improper anticoagulant
Other tests from different labs that may be relevant