Common Variable Immunodeficiency Syndrome (CVID): TNFRSF13B (TACI) (Known Mutation)
Use
This test is used when a specific known mutation in the TNFRSF13B (TACI) gene has been documented in a patient or family (index case) by the ordering physician. It enables targeted testing of that known mutation in family members, facilitating confirmation of familial immunodeficiency risk. If the mutation is not documented, a full sequencing option (test 252456) should be ordered instead.
Special Instructions
This option is available when the mutation is known and can be documented by the ordering physician. Test orders must include an attestation that the provider has the patient's informed consent for genetic testing. In family testing scenario, submit the result report of the first patient tested in the family (index case), if not performed at LabCorp. Other family members are subsequently tested for that specific mutation.
Limitations
Not provided.
Methodology
NGS
Biomarkers
LOINC Codes
- 57758-5
- 57758-5
Result Turnaround Time
21-28 days
Related Documents
For more information, please review the documents below
Specimen
Extracted DNA
Volume
Not provided
Minimum Volume
Not provided