Complement C2
Also known as: C2 Complement
Use
Assess patients with hereditary deficiency of this component or acquired decrease in its level which may be seen due to hypercatabolism in hereditary angioneurotic edema, or consumption or loss as in vasculitides, glomerulonephritides, immune complex diseases. C2 deficiency is the most common complement deficiency (1 in 10,000) and is associated with SLE.
Special Instructions
The test should be conducted with the understanding that the assay is labeled for research purposes only, and its performance characteristics have not been established by the manufacturer. The results should not be used for treatment or diagnostic purposes without confirmation from another medically established diagnostic product or procedure. This should be considered, especially when ordering the test for patients who have C2 deficiency and lupus but often have negative or low titer ANA.
Limitations
The performance characteristics of the assay used in the Complement C2 test have not been established by the manufacturer and are labeled for research purposes only. Therefore, the results should not be used for treatment or for diagnostic purposes without further confirmation through other medical diagnostic procedures. This limitation is essential when interpreting the test results because they may not accurately detect or quantify C2 levels in all cases, leading to potential misdiagnosis.
Methodology
Immunoassay (Immunoassay)
Biomarkers
LOINC Codes
- 4484-2
- 4484-2
Result Turnaround Time
6-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.1 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells.
Storage Instructions
Room temperature
Causes for Rejection
Excessive hemolysis; plasma specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 12 days |
| Refrigerated | 12 days |
| Frozen | 12 days |