Congenital Adrenal Hyperplasia (CAH) Pediatric Profile Six−Comprehensive Screen (Endocrine Sciences)
Use
The Congenital Adrenal Hyperplasia (CAH) Pediatric Profile Six is a comprehensive screen designed to evaluate adrenal function in pediatric patients. It is primarily used for diagnosing and managing CAH, a genetic disorder affecting steroid hormone production. By measuring specific hormones in the serum, the profile helps detect enzyme deficiencies involved in CAH, supporting early diagnosis and treatment decisions to manage symptoms and prevent complications.
Special Instructions
Not provided.
Limitations
The test requires precise specimen handling to ensure accuracy. Minimum volume requirements cannot accommodate repeat testing, which may impact result confirmation if retesting is necessary. The long turnaround time entails planning for timely follow-up actions based on results, considering variability in testing schedules and potential need for confirmatory assays.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 79221-8 - Steroid Fract Pnl SerPl
- 6765-2 - 17OH-Preg SerPl-mCnc
- 1656-8 - 11DOC SerPl-mCnc
- 1854-9 - Androst SerPl-mCnc
- 2143-6 - Cortis SerPl-mCnc
- 2193-1 - DHEA SerPl-mCnc
- 2986-8 - Testost SerPl-mCnc
- 1668-3 - 17OHP SerPl-mCnc
- 2839-9 - Progest SerPl-mCnc
- 1657-6 - 11DC SerPl-mCnc
Result Turnaround Time
8-15 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
2 mL
Container
Red-top tube only. Do not use gel-barrier tube.
Collection Instructions
Serum must be separated from cells within 45 minutes of venipuncture. Send serum in a plastic transport tube.
Storage Instructions
Freeze. Stable at room temperature for four hours or refrigerated for one day. Stable for 90 days frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Stable for four hours |
| Refrigerated | Stable for one day |
| Frozen | Stable for 90 days |
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