Creatinine Clearance With Body Surface Area Normalization

Casandra

Casandra Test Code LC24133Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 276024CPT Code 82575

Creatinine Clearance With Body Surface Area Normalization

Also known as: Clearance, Creatinine

Clinical Use

Order Test

Use

The Creatinine Clearance with Body Surface Area Normalization test is used to evaluate kidney function by measuring how effectively creatinine, a waste product of muscle metabolism, is cleared from the blood by the kidneys. This test helps in assessing glomerular filtration rate (GFR), providing critical information for diagnosing and managing conditions affecting kidney health, such as chronic kidney disease (CKD). By including body surface area normalization, the test accounts for variations in patients' sizes, offering a more standardized assessment of kidney function.

Special Instructions

Not provided.

Limitations

Creatinine clearance estimation may be influenced by factors other than glomerular function, such as muscle mass and diet. This test may not fully reflect kidney function in patients with muscle wasting or those on specific diets. Medications like cephalosporins can interfere with creatinine measurements, potentially leading to inaccurate results. Proper patient preparation and adherence to guidelines are crucial.

Test Details

Methodology

Automated Analyzer (Clinical Chemistry)

Biomarkers

Body Surface AreaCreatinine ClearanceSerum creatinineUrine creatinine

LOINC Codes

Order Codes

34555-3 - Creat 24H Cl Pnl Ur+SerPl

Result Codes

2160-0 - Creat SerPl-mCnc
2161-8 - Creat Ur-mCnc
2162-6 - Creat 24h Ur-mRate
2164-2 - Creat Cl 24h Ur+SerPl-vRate
3141-9 - Weight Measured
3137-7 - Body height Measured
8277-6 - BSA
98979-8 - eGFRcr SerPlBld CKD-EPI 2021

Result Turnaround Time

1 day

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube

Collection Instructions

Separate serum from cells within 45 minutes of collection. Submit both urine and serum simultaneously. It is preferable to collect the serum at the time the urine collection is completed or when the serum is brought to the draw station.

Patient Preparation

Patient should avoid taking cephalosporins. Have patient drink water before the clearance is begun, and continue good hydration throughout the clearance. If possible, drugs should be stopped beforehand.