Deoxypyridinoline (Dpd) Cross-links (Serial Monitor)
Use
The Dpd test can be used as a tool to assess bone resorption rates in healthy individuals and in patients with enhanced risk of developing metabolic bone disease. Significantly high levels of Dpd are found in children, in postmenopausal women due to estrogen deficiency, and in patients with diseases that have high bone turnover rates. Dpd can be used to monitor antiresorptive therapies in postmenopausal women and in individuals diagnosed with osteoporosis.
Special Instructions
The patient's Social Security number must be submitted for monitoring purposes. It is advised to avoid using different assay methods interchangeably in serial testing. Consistency in using the same assay method is recommended for monitoring a patient's therapy course.
Limitations
This test has not been proven to predict the development of osteoporosis or the risk of future fractures. Additionally, the results may not be interchangeable with results from other assay methods, and should not be interpreted as definitive evidence for the presence or absence of malignant diseases.
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 27424-1
- 27424-1
- 2161-8
- 25095-1
- 80563-0
Result Turnaround Time
4-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
10 mL
Minimum Volume
1 mL
Container
Plastic urine container, no preservative
Collection Instructions
Collection before 10 AM is recommended (e.g., first morning void). Do not add preservative.
Storage Instructions
Refrigerate.
Causes for Rejection
Gross hemolysis; gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |