Digoxin, Random
Also known as: Lanoxin®
Use
Diagnose and prevent digoxin toxicity; prevent underdosage; monitor therapeutic drug level; prevention and therapy of cardiac arrhythmias
Special Instructions
Ensure that the patient is not taking digitoxin. Biotin (Vitamin B7/B8) can interfere with the test, so patients should stop biotin consumption at least 72 hours prior to sample collection.
Limitations
Digoxin should not be mistaken for digitoxin. Patients with renal failure may have endogenous digoxin-like material in their serum causing unreliable digoxin measurements. Digoxin levels must be interpreted in the context of clinical and chemical data, as factors such as renal failure, hypercalcemia, and medication interactions can affect toxicity sensitivity.
Methodology
Other
Biomarkers
LOINC Codes
- 10535-3
- 10535-3
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.7 mL
Container
Gel-barrier tube (preferred) or red-top tube
Collection Instructions
If a red-top tube is used, transferred serum to a plastic transport tube. Random collection is used when a digoxin test is collected at a time other than the ideal collection time. Ideally, blood is drawn six to eight hours after the last dose.
Patient Preparation
Patients should stop biotin consumption at least 72 hours prior to the collection of a sample.
Storage Instructions
Store at room temperature.
Causes for Rejection
Citrate plasma specimen; improper labeling
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |