Ethylene Oxide
Use
The Ethylene Oxide test measures specific IgE antibodies associated with immune response to ethylene oxide exposure, which is of clinical significance due to potential sensitization in occupational settings. Ethylene oxide is used extensively in the medical industry for sterilization of medical equipment. The test can help identify individuals with allergic sensitization to ethylene oxide through elevated IgE levels, indicating immunological sensitization, which can be critical in diagnosing occupational allergies.
Special Instructions
This test should be ordered for individuals with a suspected allergy to ethylene oxide, particularly those in professions with high exposure risk. Ensure proper specimen collection and handling as per guidelines to avoid sample rejection. The stability of the specimen is crucial to maintain accurate results, especially if there are delays in testing due to specimen transportation logistics.
Limitations
The sensitivity and specificity of this test may be limited by cross-reactivity with other allergens leading to false-positive results. Additionally, low levels of IgE may not be detected due to assay sensitivity thresholds. The results of this test should be interpreted in the context of the patient's clinical symptoms and exposure history. This test does not diagnose ethylene oxide toxicity but instead identifies sensitization through IgE levels.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 6112-7
- 6112-7
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.2 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 3 months |