Gastrin, Five Specimens
Use
This test is used to measure the level of gastrin, a hormone that stimulates acid secretion by the stomach. Gastrin levels are often tested to help diagnose conditions involving the stomach and duodenum, such as Zollinger-Ellison syndrome or chronic atrophic gastritis. Sequential sampling allows for more detailed observation of changes in gastrin levels over time, particularly before and after a stimulating intervention.
Special Instructions
This is a sequential sampling test requiring multiple specimens to be drawn at different time points. It involves an initial baseline sample collection followed by administration of a stimulus, such as a drug or glucola. Multiple specimens are collected post-stimulation to observe changes in gastrin levels. Patients consuming high doses of biotin should refrain from doing so 72 hours prior to sample collection due to potential interference in test results.
Limitations
This test may exhibit interference if the specimen is collected from a patient consuming high doses of biotin. Ensure biotin supplementation is halted 72 hours before collection. The sequential aspect of the test requires precise timing and coordination for accurate results.
Methodology
Immunoassay (Immulite 2000 Immunochemiluminometric assay (ICMA))
Biomarkers
LOINC Codes
- 16152-1
- 16153-9
- 16154-7
- 59831-8
- 59832-6
- 46963-5
- 59831-8
- 59832-6
- 16152-1
- 16153-9
- 16154-7
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
This test requires the collection of five serum specimens at specific time intervals. Collect an initial baseline specimen before administering a drug or other stimulus. Follow with subsequent specimen collections as directed for post-stimulation evaluation.
Patient Preparation
Patients should stop biotin consumption at least 72 hours before collection.