Gastrin, Six Specimens
Use
The Gastrin, Six Specimens test is used primarily in evaluating patients for conditions related to high levels of gastrin. Gastrin is a hormone that stimulates the secretion of gastric acid, which is crucial for digestion. Multiple specimens are collected to monitor gastrin levels over time, especially after stimulating the patient with a drug or other treatment. This sequential testing can help diagnose disorders such as Zollinger-Ellison syndrome, which is characterized by excessive gastrin production, leading to peptic ulcers.
Special Instructions
This test is a part of a series panel requiring sequential specimens. An initial baseline specimen is collected, followed by additional specimens after administering a drug or treatment to the patient. It should not be used if no treatment follows the initial collection. Interference can occur if the patient is taking biotin supplements; thus, they should discontinue biotin at least 72 hours prior to sample collection. Consult the clinician before proceeding with the series.
Limitations
Potential interference from biotin supplementation, which can affect the accuracy of the results. Patients must stop biotin consumption 72 hours prior. Accurate test results depend on timing and conditions of each sample collection according to described protocols. Misinterpretation may occur without proper context or if samples are compromised.
Methodology
Immunoassay (Immulite Chemiluminometric)
Biomarkers
LOINC Codes
- 59831-8
- 46963-5
- 59832-6
- 16152-1
- 16153-9
- 16154-7
- 16155-4
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Container
Multiple tubes
Collection Instructions
Sequential sampling requiring collection of an initial tube (baseline) followed by additional tubes after treatment. Ensure no biotin is consumed by patient for at least 72 hours prior to collection.
Patient Preparation
Ask about biotin supplementation; discontinue biotin 72 hours before collection.