Glutathione, Total
Use
Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia.
Special Instructions
The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.
Limitations
Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by LabCorp, and it should not be used as a standalone diagnostic test.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 91685-8
- 2383-8
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
500 μL
Minimum Volume
100 μL
Container
Yellow-top ACD-B tube (acid citrate dextrose) or yellow-top ACD-A tube
Collection Instructions
Allow ACD tubes to fill completely; gently invert 8 to 10 times.
Storage Instructions
Room temperature
Causes for Rejection
Blood collected in tubes other than ACD tubes; ACD collection tubes inadequately filled; hemolyzed specimens; clotted specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 7 days |