Gluten, Fecal, Quantitative
Also known as: Fecal, Gluten, Gliadin 33mer, Stool, Gluten
Use
This Gluten ELISA test is intended for the quantitative determination of Gliadin 33mer in stool samples. This test may be used for the following applications:
Special Instructions
While the intestinal biopsy is the 'gold standard' for detecting mucosal damage, this non-invasive test offers a practical alternative for monitoring gluten ingestion. Persons using this test should ensure samples remain uncontaminated and handle collection carefully. Gluten in stool is detectable for up to four days post-consumption.
Limitations
This test was developed by Labcorp and has not been cleared or approved by the FDA. Serological markers like tTG IgA and EMA IgA have shown sensitivity below 50% for detecting villous atrophy in patients on a GFD. There is a significant need for more accurate monitoring methods for non-response to a GFD. While the test can indicate gluten exposure, it cannot account for all factors affecting gluten sensitivity.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 100359-9
- 100359-9
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
3 g
Minimum Volume
1 g
Container
Clean, screw-capped, plastic vial with no preservatives
Collection Instructions
Do not contaminate outside of container with specimen; do not overfill container. Loose/watery stools are acceptable. Ensure no toilet tissue/sanitary materials are present in the submitted specimen.
Storage Instructions
Refrigerate.
Causes for Rejection
Non-fecal sample received (e.g., serum, plasma, urine); stool contaminated with urine; samples from diaper unless uncontaminated; preserved stool received (e.g., 10% formalin, merthiolate formalin, sodium acetate formalin, or polyvinyl alcohol)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |