Gonadotropin-releasing Hormone
Also known as: GNRH, LHRH
Use
This test measures the level of gonadotropin‑releasing hormone (GnRH), also known as luteinizing hormone‑releasing hormone (LHRH). GnRH produced in the hypothalamus regulates the secretion of pituitary gonadotropins (LH and FSH), which are critical for pubertal development and reproductive function. Abnormal circulating GnRH levels may aid in assessment of delayed or precocious puberty and related endocrine disorders.
Special Instructions
Add aprotinin (Trasylol®) to all specimens to maintain analyte stability. Separate the plasma immediately, store, and ship it frozen. Use a chilled lavender‑top (EDTA) tube, add Trasylol®, centrifuge to obtain plasma, freeze immediately. For multiple tests on frozen specimens, submit separate frozen specimens to avoid delays.
Limitations
Not provided.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 13660-6
- 13660-6
Result Turnaround Time
8-12 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.5 mL
Container
Trasylol® collection kit (Obtain N° 33328 through LabCorp branch locations.)
Collection Instructions
Using a chilled lavender‑top (EDTA) tube, collect a whole blood specimen, add 0.25 mL of Trasylol® to the tube and mix well. Centrifuge the sample and remove the plasma. Freeze immediately. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze.
Causes for Rejection
Thawed or nonfrozen specimen; specimen type other than EDTA plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 48 hours |
| Frozen | 291 days |