Gynecologic Pap Test−Age-based Guideline for Cervical Cancer (Aptima®) and STDs
Also known as: Age-based Guideline for Cervical Cancer and STDs, Cervical Cancer Screening and STDs
Use
Diagnose primary or metastatic neoplasm; detect Chlamydia trachomatis and Neisseria gonorrhoeae. High-risk HPV test is used for types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, without differentiation of the individual type. When the age guideline includes possible genotyping, the residual specimen will be tested individually for high-risk HPV genotypes 16 and 18,45 if the Pap evaluation is within normal limits and the initial HPV test is positive. This information, together with the physician's assessment of cytology history, other risk factors, and professional guidelines, may be used to guide patient management. The results of this test are not intended to prevent women from proceeding to colposcopy.
Special Instructions
Not provided.
Limitations
Failure to obtain adequate ectocervical, endocervical, or vaginal cell population can affect evaluation. Excessive lubricating jelly use can interfere with cytologic examination. Liquid-based cytology specimens used for multiple tests may limit the volume for Pap reprocessing or HPV testing. Negative results do not rule out HPV infection due to low infection levels or sampling error. The test only detects 14 common high-risk HPV types. Special procedures are required for testing Chlamydia trachomatis and Neisseria gonorrhoeae, and cannot be added after specimen submission.
Methodology
Other
Biomarkers
Chlamydia trachomatis
OtherHPV
MicroorganismNeisseria gonorrhoeae
Other
LOINC Codes
- 47527-7 - Cytology Cvx/Vag Doc Thin Prep
- 19764-0 - Stat of Adq Cvx/Vag Cyto-Imp
- 19773-1 - Recom F/U Cvx/Vag Cyto
- 19763-2 - Specimen source Cvx/Vag Cyto
- 22636-5 - Path report.relevant Hx Spec
- 22638-1 - Path report.comments Imp Spec
- 22639-9 - Path report.supplemental reports Spec
- 19767-3 - Cytologist Cvx/Vag Cyto
- 19769-9 - Pathologist Cvx/Vag Cyto
- 8251-1 - Service Cmnt-Imp
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Not provided
Minimum Volume
Not provided
Container
ThinPrep® vial
Collection Instructions
For the broom technique, insert the device into the cervical os and rotate five times, rinsing in PreservCyt® solution. For the brush/spatula technique, insert the brush into the endocervical canal, rotate, and rinse in the solution. Ensure adequate ectocervical sample and tighten vial cap appropriately.
Patient Preparation
Avoid douches 48 to 72 hours before examination. Do not collect during or shortly after menstrual period.
Storage Instructions
Keep at room temperature. Pap processing must occur within 21 days. HPV testing must occur within three months. Testing for Chlamydia/Gonococcus within seven days.
Causes for Rejection
Improper collection; inadequate specimen; improper labeling; leaked specimen in transit; quantity not sufficient; discrepancies; specimen from male patient; expired vial; frozen specimen; unacceptable vial types.