Gynecologic Pap Test−Age-based Guideline for Cervical Cancer (Aptima®) Plus Chlamydia/Gonococcus/Trichomonas
Also known as: Age-based Guideline for Cervical Cancer Plus Chlamyda/Gonococcus/Trichomonas, Cervical Cancer Screening Plus Chlamydia/Gonococcus/Trichomonas
Use
Diagnose primary or metastatic neoplasm; detect Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis. High-risk HPV test is used for types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, without differentiation of the individual type. When the age guideline includes possible genotyping, the residual specimen will be tested individually for high-risk HPV genotypes 16 and 18,45 if the Pap evaluation is within normal limits and the initial HPV test is positive. This information, together with the physician's assessment of cytology history, other risk factors, and professional guidelines, may be used to guide patient management. The results of this test are not intended to prevent women from proceeding to colposcopy.
Special Instructions
Not provided.
Limitations
The test's sensitivity might be limited by inadequate specimen collection or the presence of lubricating jelly. Very low levels of infection or sampling errors could result in false-negative results, especially with HPV testing. The liquid-based cytology specimen's use for multiple tests may limit the available volume for reprocessing. This test detects only the 14 most common high-risk HPV types. Reflex genotyping for specific HPV types may be required based on patient age and initial test results. Specimens require special processing and cannot have tests added post-submission.
Methodology
Other
Biomarkers
LOINC Codes
- 47527-7 - Cytology Cvx/Vag Doc Thin Prep
- 19764-0 - Stat of Adq Cvx/Vag Cyto-Imp
- 19773-1 - Recom F/U Cvx/Vag Cyto
- 22636-5 - Path report.relevant Hx Spec
- 22638-1 - Path report.comments Imp Spec
- 22639-9 - Path report.supplemental reports Spec
- 50387-0 - C trach rRNA Cvx Ql NAA+probe
- 50388-8 - N gonorrhoea rRNA Cvx Ql NAA+probe
- 46154-1 - T vaginalis rRNA Spec Ql NAA+probe
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Cervical Swab
Volume
ThinPrep® vial
Minimum Volume
Not provided
Container
ThinPrep® vial
Collection Instructions
Use a broom or brush/spatula technique to collect the specimen. For both methods, rinse the collection device in the PreservCyt® solution and ensure the cap is tightly secured on the ThinPrep® vial.
Patient Preparation
Avoid douches 48 to 72 hours before the examination. Do not collect the specimen during or shortly after a menstrual period.
Storage Instructions
Maintain liquid-based cytology specimen at room temperature. Test within specified timeframes: 21 days for Pap, three months for HPV, and seven days for Chlamydia/Gonococcus/Trichomonas.
Causes for Rejection
Causes for rejection include improper collection, inadequate specimen, improper labeling, leakage in transit, insufficient quantity, name discrepancies, expired vials, frozen specimens, and submissions on male patients.