Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Chlamydia/Gonococcus/Trichomonas, NAA With Reflex to Human Papillomavirus (HPV) (Aptima®) When ASC-U, ASC-H, LSIL, HSIL, AGUS
Use
Diagnose primary or metastatic neoplasm; detect Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis. This test aids in the diagnosis of sexually transmitted HPV infection. High-risk HPV test is used for types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, without differentiation of the individual type.
Special Instructions
Not provided.
Limitations
Failure to obtain an adequate ectocervical, endocervical, or vaginal cell population is suboptimal for evaluation. Excessive use of lubricating jelly can interfere with examination leading to unsatisfactory results. The liquid-based specimen used for multiple tests may limit available volume for Pap reprocessing or HPV testing. A negative result does not completely exclude an HPV infection as low infection levels or sampling errors can lead to false negatives. This test detects only the 14 most common high-risk HPV types and cannot specify the HPV type present. Testing for the organisms requires special specimen processing, which cannot be added after initial submission.
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 47527-7 - Cytology Cvx/Vag Doc Thin Prep
- 47528-5 - Cytology Cvx/Vag Doc Cyto
- 19764-0 - Stat of Adq Cvx/Vag Cyto-Imp
- 19763-2 - Specimen source Cvx/Vag Cyto
- 52797-8 - Dx ICD code
- 22636-5 - Path report.relevant Hx Spec
- 19769-9 - Pathologist Cvx/Vag Cyto
- 11546-9 - Other Stn Spec
- 50387-0 - C trach rRNA Cvx Ql NAA+probe
- 50388-8 - N gonorrhoea rRNA Cvx Ql NAA+probe
- 46154-1 - T vaginalis rRNA Spec Ql NAA+probe
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Cervical Swab
Volume
ThinPrep® vial
Minimum Volume
Not provided
Container
ThinPrep® vial
Collection Instructions
Broom-like collection technique: Obtain a sample using a broom-like device, insert into the cervical os, rotate five times, and rinse the collection device in the PreservCyt® solution by pushing the brush 10 times into the bottom of the vial.
Patient Preparation
Patient should avoid douches 48 to 72 hours prior. Do not collect during or shortly after menstrual period.
Storage Instructions
Maintain specimens at room temperature. Pap processing must be within 21 days of collection; specimens in ThinPrep® vials must be processed for HPV testing within 21 days.
Causes for Rejection
Improper collection, inadequate specimen, improper labeling, leaked specimen, insufficient quantity, name discrepancies, submission on male patient, expired vial, frozen specimen, or SurePath™ vial are causes for rejection.