Gynecologic Pap Test, Liquid-based Preparation and Chlamydia trachomatis, NAA
Also known as: Chlamydia trachomatis, Aptima® TMA, Liquid-based Pap, Out-of-the-vial Testing
Use
Diagnose primary or metastatic neoplasma; detect Chlamydia trachomatis
Special Instructions
Not provided.
Limitations
An inadequate collection of ectocervical, endocervical, or vaginal cell populations can compromise the evaluation. Using excessive lubricating jelly on the vaginal speculum may interfere with cytological examination, leading to unsatisfactory results. Testing for Chlamydia trachomatis requires specific processing of the cytology specimen; it cannot be added after specimen submission. Cross-specimen contamination is a risk when using transport devices for molecular testing; however, Aptima® transports help minimize this risk by directly interfacing with analyzers.
Methodology
PCR-based (Nucleic Acid Amplification (NAA))
Biomarkers
LOINC Codes
- 11546-9 - Other Stn Spec
- 52797-8 - Dx ICD code
- 50387-0 - C trach rRNA Cvx Ql NAA+probe
- 19764-0 - Stat of Adq Cvx/Vag Cyto-Imp
- 47527-7 - Cytology Cvx/Vag Doc Thin Prep
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Cervical Swab
Volume
ThinPrep® vial or ThinPrep® vial with optional additional Aptima® swab collection kit (for Chlamydia)
Minimum Volume
Not provided
Container
ThinPrep® vial or ThinPrep® vial and Aptima® swab collection kit (for Chlamydia)
Collection Instructions
Cervical cells should be collected using either a broom or brush/spatula technique. For Chlamydia, use the Gen-Probe® Aptima® swab. Avoid using the Gen-Probe® PACE DNA probe collection kit. Collection involves proper handling and transfer to the respective containers.
Patient Preparation
Patients should avoid douches 48 to 72 hours prior to examination. Samples should not be collected during or shortly after the menstrual period.
Storage Instructions
Maintain liquid-based cytology and Aptima® swab transport specimens at room temperature; Pap processing within 21 days; cytology specimens for Chlamydia testing within seven days, Aptima® swabs within 60 days.
Causes for Rejection
Rejection can occur due to improper collection, inadequate specimen, improper labeling, leaks in transit, or insufficient quantity for analysis. Other causes include specimen from male patients, expired collection vials, frozen specimens, and use of non-approved swabs.