Hepatitis B Core Antibody, IgM

Also known as: Anti-HBc, IgM, Antibody to Hepatitis B Core Antigen, IgM, HBV

Clinical Use

Use

This assay may be used in combination with other hepatitis B virus (HBV) marker assays to define the clinical status of known HBV infected patients or can be combined with other HBV, HAV (hepatitis A virus), and HCV (hepatitis C virus) assays for the diagnosis of patients presenting with symptoms of acute viral hepatitis.

Special Instructions

Not provided.

Limitations

Assay performance characteristics have not been established for immunocompromised or immunosuppressed patients, cord blood, or patients less than 2 years of age. Heterophilic antibodies in human serum can react with reagent immunoglobulins, interfering with in vitro immunoassays. Patients routinely exposed to animals or to animal serum products can be prone to this interference and anomalous values may be observed. A reactive anti-HBc IgM result does not exclude co-infection by another hepatitis virus. Assay performance characteristics have not been established when the ADVIA Centaur HBc IgM assay is used in conjunction with other manufacturers' assays for specific HBV serological markers.

Test Details

Methodology

Immunoassay (CLIA)

Biomarkers

Hepatitis B Core Antibody, IgM

Protein

Immunoassay

Expression • Categorical (e.g., Positive / Negative / Indeterminate)

LOINC Codes

Order Codes

24113-3 - HBV core IgM SerPl Ql IA

Result Codes

24113-3 - HBV core IgM SerPl Ql IA

Result Turnaround Time

1-2 days

Specimen

Serum

Volume

1 mL

Minimum Volume

0.4 mL

Container

Gel-barrier tube, red-top tube or serum transfer tube

Collection Instructions

If tube other than a gel-barrier tube is used, transfer separated serum to a screw-cap polypropylene transport tube. Do not freeze gel-barrier tube (pour off serum first).