HER-2/neu, Serum

Casandra

Casandra Test Code LC30545Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 480136CPT Code 83950

Also known as: HER-2 Extracellular Domain (ECD), HER-2/neu Shed Antigen

Clinical Use

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Use

Quantitative measure of HER-2/neu in human serum. HER-2/neu values obtained may be used in the follow-up and monitoring of patients with metastatic breast cancer. HER-2/neu values should be used in conjunction with information available from clinical and other diagnostic procedures in the management of breast cancer. The clinical utility of the measurement of HER-2/neu as a prognostic indicator for early recurrence and in the management of patients on immunotherapy regimens has not been fully established.

Special Instructions

Not provided.

Limitations

Elevated levels of serum HER-2/neu are observed in a subset of patients with HER-2/neu-positive tumors. Approximately 25% to 30% of breast cancers demonstrate overexpression of the HER-2/neu protein. The clinical utility of the measurement of HER-2/neu as a prognostic indicator for early recurrence and in the management of patients on immunotherapy regimens has not been fully established.

Test Details