Hereditary Hemochromatosis, DNA Analysis
Also known as: Cirrhosis, Iron Overload, Iron Storage
Use
Aids in the identification of individuals at risk for symptoms of hemochromatosis due to variants in the HFE gene.
Special Instructions
Not provided.
Limitations
Results should be combined with clinical information for accurate interpretation. As with any laboratory test, there is a possibility of rare diagnostic errors. False positive or false negative results may arise from genetic variants, blood transfusions, bone marrow transplantation, somatic or tissue-specific mosaicism, mislabeled samples, or incorrect family relationship representation. Molecular-based testing is generally highly accurate but not immune to errors.
Methodology
PCR-based (PCR)
Biomarkers
No genes
Gene
LOINC Codes
- 34519-9 - HFE gene Mut Anl Bld/T
- 34519-9 - HFE gene Mut Anl Bld/T
- 56850-1 - Imp & review of lab results
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
7 mL
Minimum Volume
3 mL
Container
Lavender-top (EDTA) tube
Storage Instructions
Maintain specimen at room temperature or refrigerate.
Causes for Rejection
Frozen specimen; hemolysis; quantity not sufficient for analysis; improper container.
Other tests from different labs that may be relevant