Herpes Simplex Virus (HSV) Culture and Typing
Also known as: ELVIS® HSV, Five- to Seven-day Herpesvirus Culture/Type, HSV Culture and Typing, Viral Culture, HSV, Virus Isolation, Herpes Simplex
Use
The Herpes Simplex Virus (HSV) Culture and Typing test is designed to detect and identify the type of HSV infection in patients. HSV is a common virus that causes infections in various parts of the body and can lead to conditions such as cold sores and genital herpes. Accurate identification of the type of HSV infection can guide appropriate treatment and management, helping to prevent transmission and recurrence. The test is particularly useful for diagnosing HSV in cases of suspected encephalitis, meningitis, and neonatal infections, where rapid and precise detection is critical for clinical decision-making.
Special Instructions
Submit one specimen per test requested. Specify the exact specimen source/origin, e.g., genital lesion. Indicate a specific test number on the request form. Check expiration date of the transport media; do not use expired devices. After collection, ensure the correct procedures are followed for transporting and storing samples to maintain integrity before testing.
Limitations
Infectious HSV is rarely present in CSF during encephalitis, resulting in poor recovery by culture (<5% in adults, <50% in children). PCR testing offers better detection in such cases. Specimen quality and timing of collection are crucial for accurate results, as improper handling can lead to false negatives. Specimen must be kept refrigerated and transported in appropriate viral transport media to preserve viral integrity.
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 5859-4
- 5859-4
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Vaginal Swab
Volume
Swab in viral transport media
Minimum Volume
Not provided
Container
Viral, Chlamydia, or Mycoplasma culture transport
Collection Instructions
Specimen is best collected within the first three days after appearance of lesion but not more than seven days. After collection, insert swab into transport tube, break swab shaft, and label with patient identification. Transport to laboratory at 4°C.
Storage Instructions
Refrigerate.
Causes for Rejection
Bacterial swab specimen; specimen received in grossly leaking transport container; dry specimen; specimen submitted in fixative or additive; specimen received in expired transport media or incorrect transport device; inappropriate specimen transport conditions; specimen stored or transported greater than seven days refrigerated; specimen stored or transported at room temperature; wooden shaft swab in transport device; unlabeled specimen or name discrepancy between specimen and test request label
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |