Histoplasma Galactomannan Antigen EIA, Urine
Also known as: Histoplasma Galactomannan Antigen EIA, Histoplasma Urinary Antigen
Use
Diagnosis of histoplasmosis based upon detection of antigen
Special Instructions
Refrigerate urine specimens immediately after collection. Use sterile containers and maintain cleanliness to avoid contamination. In cases where endemic mycoses or other fungal infections are prevalent, confirmatory testing may be necessary due to possible cross-reactivity.
Limitations
A negative result does not rule out histoplasmosis, as antigen levels may be undetectable, particularly in chronic conditions with low fungal burden. Positive results should be interpreted with caution in geographical regions where cross-reacting fungi like Blastomyces dermatitidis, Coccidioides immitis, Paracoccidioides brasiliensis, and Penicillium marneffei are endemic. Substances such as foods that stain urine, vaginal creams, various medications, and chemicals may interfere with the assay results.
Methodology
Immunoassay (EIA)
Biomarkers
LOINC Codes
- 48952-6
- 44524-7
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
1 mL
Container
Sterile cup or sterile screw-capped vial
Collection Instructions
Collect specimen aseptically
Storage Instructions
Refrigerate. Store specimens at 2°C to 8°C or frozen at -16°C to 24°C for up to 14 days.
Causes for Rejection
Specimen not refrigerated or frozen; insufficient specimen volume; inappropriate specimen source; inappropriate specimen collection device; specimen stability exceeded; name discrepancy between the specimen container and requisition
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |