HLA B*57:01, Abacavir Hypersensitivity HLA Association Test
Also known as: Abacavir Hypersensitivity HLA Association, B*5701, B*57:01, B5701, HLA Antigen B*57:01
Use
Determine the presence of B57 antigen
Special Instructions
If you have questions, please telephone 800-533-1037 (HLA customer service) for assistance in selecting the proper HLA test for the patient. There is a requirement for specific collection materials, such as a buccal swab kit provided by LabCorp, which can be obtained by contacting customer service at the provided number.
Limitations
Even with appropriate precautions, an occasional specimen may not be satisfactory for testing. In such cases, an additional specimen should be collected for testing. Moreover, a negative result for HLA-B*57:01 does not preclude the possibility of developing an allergic response to abacavir. The genotype result should not substitute for clinical vigilance and patient management in abacavir-containing regimens.
Methodology
PCR-based (SSOP)
Biomarkers
LOINC Codes
- 42358-2
- 42358-2
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
7 mL
Minimum Volume
3 mL
Container
Lavender-top (EDTA) tube
Storage Instructions
Maintain blood specimen at room temperature.
Causes for Rejection
Hemolysis; clotted specimen; insufficient amount of DNA on buccal swabs