Human Herpesvirus 6 (HHV-6), DNA PCR
Also known as: HHV-6 DNA PCR, HHV6, Human Herpesvirus Type 6 DNA PCR
Use
This test is intended to be used as an aid in the diagnosis of infection with human herpesvirus 6 (HHV-6).
Special Instructions
The test employs Real-time polymerase chain reaction (PCR) methodology and requires specimens to be maintained at room temperature or refrigerated. It's important to note that cerebrospinal fluid (CSF) samples can be frozen, however, whole blood cannot be subjected to freezing. Ensure that specimens are not grossly contaminated or inadequately filled to avoid rejection.
Limitations
The test was developed and its performance characteristics were determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration, which may affect its acceptance in some clinical settings. Additionally, the test's sensitivity and specificity were not detailed in the product description, and there may be limitations in detecting low viral loads or variant strains of the virus due to its reliance on PCR. Testing schedules may vary, which could result in longer turnaround times for confirmatory tests if reflex testing is required.
Methodology
PCR-based (Real-time PCR)
Biomarkers
LOINC Codes
- 29495-9
- 29495-9
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.2 mL
Container
Sterile container
Storage Instructions
Maintain specimen at room temperature or refrigerate. CSF can be frozen, whole blood cannot be frozen.
Causes for Rejection
Quantity not sufficient for analysis; gross specimen contamination; specimen too old; leaking or broken tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 90 days, CSF only (whole blood cannot be frozen) |