Human Immunodeficiency Virus 1 (HIV-1) Trofile® DNA (Monogram® Coreceptor Tropism), Whole Blood
Use
Detect HIV-1 coreceptor tropism; determine eligibility for CCR5 antagonist therapy such as Selzentry™ (maraviroc).
Special Instructions
Not provided.
Limitations
This test should be used only for patients with documented HIV-1 infection and undetectable viral loads. It has been developed and its performance characteristics determined by Labcorp. However, it has not been cleared or approved by the Food and Drug Administration, which may limit its use in certain clinical settings.
Methodology
PCR-based
Biomarkers
CCR5 Co-receptor
AnalyteCXCR4 Co-receptor
Analyte
LOINC Codes
- 51969-4 - Gene analysis narr rpt Doc
- 80690-1 - HIV1 proviral DNA tropism Bld MC
- 50790-5 - HIV1 RNA tropism Islt
- 62364-5 - Test performance info Spec
Result Turnaround Time
29-33 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tube
Collection Instructions
Collect specimen in lavender-top (EDTA) tube. Do not centrifuge. Ship frozen. To avoid delays in turnaround time, when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze.
Causes for Rejection
Insufficient volume; heparinized plasma; nonfrozen specimen
Other tests from different labs that may be relevant