Insulin, Two Specimens

Clinical Use

Use

The Insulin, Two Specimens test is designed for assessing insulin levels at multiple points during a stimulation or suppression test. This test involves collecting a baseline serum specimen and additional specimens at various intervals after administering a treatment, such as a drug or glucose. It helps in evaluating insulin production dynamics, identifying potential insulin resistance, and assisting in the diagnosis of conditions such as insulinomas or hypoglycemia.

Special Instructions

Not provided.

Limitations

This test may demonstrate interference in patients taking high doses of biotin (vitamin B7, B8, H, or coenzyme R). Precaution is needed to ensure continued biotin avoidance to avoid skewed results. The test should only be ordered when the treatment plan confirms an intervention is administered during the collection process. External factors including improper labeling, incorrect patient preparation, or handling of specimens may impact results.

Test Details

Methodology

Immunoassay (CLIA)

Biomarkers

Insulin #1

Analyte

Insulin #1

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Insulin #2

Analyte

Insulin #2

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

20448-7 - Insulin SerPl-aCnc
46963-5 - Tube # SerPlBld

Result Codes

20448-7 - Insulin SerPl-aCnc
46963-5 - Tube # SerPlBld
33816-0 - Insulin sp2 p chal SerPl-aCnc

Result Turnaround Time

1-2 days

Specimen

Serum

Volume

2 mL

Minimum Volume

Not provided

Collection Instructions

Separate serum from cells within 45 minutes of venipuncture. Label each tube with patient name and time interval. Submit simultaneously from the same patient on one test request form.