Intrauterine Fetal Demise/Stillborn Profile (Extended)
Use
A recent American Congress of Obstetricians and Gynecologists (ACOG) practice bulletin made recommendations as to the appropriate use of laboratory tests that should be performed as part of the investigation of the cause of late term (greater than 20 weeks) fetal demise.6 The authors suggested that maternal testing for thyroid stimulating hormone (TSH), human parvovirus B19 IgG and IgM, lupus anticoagulants, and anticardiolipin antibodies could provide useful information for future pregnancy management.
Special Instructions
Avoid taking warfarin (Coumadin®) for two weeks and heparin therapy for two days prior to the test to ensure accurate results. Double centrifugation is required for citrate plasma specimens, and these must be frozen immediately after collection.
Limitations
The test relies on accurate sample collection and preparation, particularly for citrate plasma which requires specific handling to avoid contamination. The interpretation of results should be integrated with clinical information as variables such as genetic predispositions and environmental factors can affect results.
Methodology
PCR-based
Biomarkers
LOINC Codes
- 13965-9
- 11580-8
- 20507-0
- 5273-8
- 5274-6
- 27811-9
- 27818-4
- 27821-8
- 34571-0
- 6303-2
- 75514-0
- 3181-5
- 3182-3
- 21667-1
- 24476-4
- 6690-2
- 789-8
- 718-7
- 4544-3
- 787-2
- 785-6
- 786-4
- 788-0
- 777-3
- 770-8
- 736-9
- 5905-5
- 713-8
- 706-2
- 71695-1
- 53115-2
- 58413-6
- 18314-5
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL serum
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate
