Manganese, Urine
Also known as: Mn, Urine
Use
Confirm manganese exposure, toxicity, or poisoning by documenting excessive urine excretion of the metal. Also used to individualize manganese dosing in long-term parenteral nutrition, especially in liver disease, when biliary excretion is low, or when there is excessive gastrointestinal losses, such as in short bowel syndrome. Has been used to follow the success of chelation therapy with para-aminosalicylate sodium in manganism.
Special Instructions
Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (such as Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.
Limitations
Levels in urine are so low that considerable error may be introduced by contamination. Manganese toxicity may leave residual neurologic damage after serum and urine levels have returned to normal, masking the original cause. This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 58736-0
- 5684-6
- 2161-8
- 27367-2
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
20 mL
Minimum Volume
1.7 mL
Container
Plastic urine container, no preservative
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |