MaterniT21 Genome Add On
Use
The MaterniT Genome test provides comprehensive chromosome copy number analysis including unbalanced derivatives, and information about deletions or duplications of chromosome material 7 Mb or larger, as well as analysis of seven clinically relevant microdeletions less than 7 Mb in size.
Special Instructions
Not provided.
Limitations
These tests are highly accurate but may yield discordant or inaccurate results due to factors such as placental, maternal, or fetal mosaicism, vanishing twin, prior maternal organ transplant, or more. The test is not validated for multifetal gestations and cannot replace CVS or amniocentesis. It does not assure against other chromosomal abnormalities or birth defects, and maternal conditions or medications may impact results. Pregnancy decisions should not rely solely on this test; genetic counseling is recommended for positive results.
Methodology
NGS (Targeted)
Biomarkers
No genes
GeneUnknown CNV
Copy Number Region
LOINC Codes
- 53693-8 - GA Est from conception date
- 75605-6 - cfDNA.fet/cfDNA.total SFr Fetus
- 75980-3 - Fet 13+18+21+X+Y aneup Plas.cfDNA
- 72486-4 - Lab director name Provider
- 75558-7 - Fet Ts 18 risk WBC.DNA+cfDNA Ql
- 73824-5 - Fet Ts 13 risk Plas.cfDNA Ql
- 75693-2 - Fet sex Plas.cfDNA Dosage cfDNA
- 75570-2 - Fet Ms X risk WBC.DNA+cfDNA Ql
- 79211-9 - Fet X + Y aneup risk Plas.cfDNA Seq-Imp
- 92903-4 - Fet Chr 15q11 Del Plas.cfDNA Ql
- 92899-4 - Fet Chr 11q23 Del Plas.cfDNA Ql
- 92902-6 - Fet Chr 8q24 Del Plas.cfDNA Ql
- 92900-0 - Fet Chr 4p16 Del Plas.cfDNA Ql
- 75602-3 - Fet 1p36 del risk WBC.DNA+cfDNA Ql
- 77202-0 - Laboratory comment Report
- 49549-9 - Ref lab test method
- 62364-5 - Test performance info Spec
- 8251-1 - Service Cmnt-Imp
- 75608-0 - Citation Ref Lab Test
- 51969-4 - Gene analysis narr rpt Doc
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
Not provided
Container
Black-and-tan-top (Streck) tube
Collection Instructions
Only the Sequenom collection kit (PeopleSoft No. 116373) can be used for collection.
Storage Instructions
Room temperature. Do not refrigerate or freeze. Keep out of direct sunlight. Samples must be shipped to LabCorp in a Sequenom collection kit.
Causes for Rejection
Gestational age less than nine weeks; expired or incorrect blood tubes; quantity not sufficient; received more than seven days from collections; excessive hemolysis; frozen specimens
Other tests from different labs that may be relevant