MaterniT21 Genome NO Gender
Use
The MaterniT Genome test provides comprehensive chromosome copy number analysis including unbalanced derivatives and, information about deletions or duplications of chromosome material 7 Mb or larger, as well as analysis of seven clinically relevant microdeletions less than 7 Mb in size.
Special Instructions
Not provided.
Limitations
While the results of these tests are highly accurate, discordant results may occur due to factors such as placental, maternal, or fetal mosaicism; prior maternal organ transplant; or maternal neoplasms. The test is not validated for multiple gestations and multifetal samples are excluded from processing. These are screening tests and should not replace prenatal diagnosis methods such as CVS or amniocentesis. Factors affecting the results include maternal BMI, systemic conditions like lupus, and certain pharmaceuticals. Results should be discussed with a qualified healthcare provider and should not be solely used for pregnancy management decisions.
Methodology
NGS
Biomarkers
LOINC Codes
- 53693-8 - GA Est from conception date
- 75605-6 - cfDNA.fet/cfDNA.total SFr Fetus
- 75980-3 - Fet 13+18+21+X+Y aneup Plas.cfDNA
- 72486-4 - Lab director name Provider
- 75983-7 - Fet Chr 21 Ts Plas.cfDNA Ql
- 75558-7 - Fet Ts 18 risk WBC.DNA+cfDNA Ql
- 73824-5 - Fet Ts 13 risk Plas.cfDNA Ql
- 75570-2 - Fet Ms X risk WBC.DNA+cfDNA Ql
- 79211-9 - Fet X + Y aneup risk Plas.cfDNA Seq-Imp
- 75578-5 - Fet 22q11.2 del risk WBC.DNA+cfDNA Ql
- 92903-4 - Fet Chr 15q11 Del Plas.cfDNA Ql
- 92899-4 - Fet Chr 11q23 Del Plas.cfDNA Ql
- 92902-6 - Fet Chr 8q24 Del Plas.cfDNA Ql
- 92900-0 - Fet Chr 4p16 Del Plas.cfDNA Ql
- 75602-3 - Fet 1p36 del risk WBC.DNA+cfDNA Ql
Result Turnaround Time
5-8 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
5 mL
Container
Black-and-tan-top (Streck) tube
Collection Instructions
Only the Sequenom collection kit (PeopleSoft No. 116373) can be used for collection.
Storage Instructions
Room temperature. Do not refrigerate or freeze. Keep out of direct sunlight.
Causes for Rejection
Gestational age less than nine weeks; expired or incorrect blood tubes (including nonglass tubes); quantity not sufficient for analysis; received more than seven days from collections; excessive hemolysis; frozen specimens
Other tests from different labs that may be relevant