Special Instructions

The following information must be provided with the test request form: patient's date of birth, gestational age, additional patient demographic information, pregnancy type (singleton or multiple), donor egg status, and the clinical indications (including advanced maternal age, abnormal ultrasound, history suggestive of increased risk for aneuploidy, positive serum screen, or other indications).

Limitations

While the results of these tests are highly accurate, discordant results, including inaccurate fetal sex prediction, may occur due to placental, maternal, or fetal mosaicism or neoplasm; vanishing twin; prior maternal organ transplant; or other causes. cfDNA testing does not replace prenatal diagnosis with CVS or amniocentesis. A patient with a positive or high-risk score test result should be referred for genetic counseling. This test cannot identify pregnancies at risk for neural tube defects or ventral wall defects. cfDNA testing for whole chromosome abnormalities could discover both fetal and maternal genomic abnormalities with minor or no clinical significance. Evaluating the significance of a positive or non-reportable test result may require invasive prenatal testing and additional studies on the mother, which might reveal maternal chromosomal abnormalities associated with benign or malignant neoplasms.

Biomarkers

LOINC Codes

Result Turnaround Time

Related Documents