MaterniT21 PLUS Core + SCA, NO Gender
Use
For pregnancies at increased risk of fetal abnormalities, the MaterniT21 PLUS test delivers a comprehensive NIPT for the analysis of chromosomal regions including trisomies 21, 18, and 13, and sex chromosome aneuploidies.
Special Instructions
Not provided.
Limitations
The results, while highly accurate, can be affected by conditions such as placental, maternal, or fetal mosaicism or neoplasm, vanishing twin syndrome, prior maternal organ transplant, and maternal weight. cfDNA testing is limited in its ability to detect neural tube defects, ventral wall defects, fetal triploidy, or precise subchromosomal duplications or deletions. A positive result should prompt genetic counseling and possibly additional invasive testing like CVS or amniocentesis.
Methodology
NGS (Targeted)
Biomarkers
Trisomy 13
OtherTrisomy 18
OtherTrisomy 21
Other
LOINC Codes
- 53693-8 - GA Est from conception date
- 75605-6 - cfDNA.fet/cfDNA.total SFr Fetus
- 75980-3 - Fet 13+18+21+X+Y aneup Plas.cfDNA
- 72486-4 - Lab director name Provider
- 75983-7 - Fet Chr 21 Ts Plas.cfDNA Ql
- 75558-7 - Fet Ts 18 risk WBC.DNA+cfDNA Ql
- 73824-5 - Fet Ts 13 risk Plas.cfDNA Ql
- 75693-2 - Fet sex Plas.cfDNA Dosage cfDNA
- 75570-2 - Fet Ms X risk WBC.DNA+cfDNA Ql
- 79211-9 - Fet X + Y aneup risk Plas.cfDNA Seq-Imp
- 75608-0 - Citation Ref Lab Test
- 8251-1 - Service Cmnt-Imp
- 51969-4 - Gene analysis narr rpt Doc
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
5 mL
Container
Black-and-tan-top (Streck) tube
Collection Instructions
Only the Sequenom collection kit PS#116373 can be used for collection.
Storage Instructions
Room temperature. Do not refrigerate or freeze. Keep out of direct sunlight. Samples must be shipped to LabCorp in a Sequenom collection kit.
Causes for Rejection
Gestational age less than nine weeks; expired or incorrect blood tubes (including nonglass tubes); quantity not sufficient for analysis; received more than seven days from collections; excessive hemolysis; frozen specimens
Other tests from different labs that may be relevant