Measles (Rubeola), PCR, Swab
Use
The Measles (Rubeola) PCR test is used as the preferred method for detecting measles in patients with compatible symptoms (fever, malaise, cough, coryza and/or conjunctivitis).
Special Instructions
Specimens should be collected as soon as possible after the development of a rash to maximize the sensitivity of measles RNA detection. Throat specimen collection is preferred to improve test accuracy.
Limitations
A negative test result does not rule out infection with measles virus. Results should be interpreted in the context of clinical findings and serological testing. Improperly collected samples may yield false negative results. Sensitivity may be reduced if samples are not collected in the recommended timeframe or if viral variants affect assay performance.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 91077-8
- 91077-8
Result Turnaround Time
3 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
One swab
Minimum Volume
One swab
Container
Viral Transport Media (VTM) or Universal Transport Media (UTM)
Collection Instructions
Throat specimen (preferred): Collect the specimen by swabbing the posterior pharynx. Nasopharyngeal swab: Collect the NP swab using standard techniques.
Storage Instructions
Refrigerated or frozen
Causes for Rejection
Improperly submitted specimens; specimen not received in an approved VTM/UTM; swabs received in Liquid Amies (E-Swabs) or other bacterial swabs; specimens received without a swab; grossly leaking specimens; specimens received outside the stated stability
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 14 days |