Mycobacterium tuberculosis Susceptibility, Broth Dilution and Confirmation
Also known as: AFB Susceptibility Testing, Susceptibility Testing, M tuberculosis, TB Susceptibility Testing
Use
Determine the susceptibility of Mycobacterium tuberculosis to a profile of antimycobacterial agents.
Special Instructions
Isolates found to be resistant will have the resistance confirmed by the agar proportion method. Susceptibilities are performed based on state regulations and statutes, and should be performed on the first organism isolated at an institution and at one and three-month intervals if the organism continues to be isolated during therapy.
Limitations
Susceptibilities cannot be reported if the organism fails to grow in the test medium, and cannot be performed on mixed cultures. Nontuberculosis Mycobacteria, particularly strains of the M avium complex, are resistant to drugs used for M tuberculosis therapy.
Methodology
Culture-based
Biomarkers
LOINC Codes
- 9825-1
- 48177-0
- 25217-1
- 25202-3
- 25194-2
- 25229-6
Result Turnaround Time
30-40 days
Related Documents
For more information, please review the documents below
Specimen
Cultured Cells
Volume
AFB conventional solid medium or 1 mL of AFB broth medium
Minimum Volume
Not provided
Container
Conventional or broth medium, tightly sealed, in etiologic agent packaging
Storage Instructions
Maintain media at room temperature
Causes for Rejection
Specimen received leaking or in broken transport tube or vial; specimen received in expired transport medium; mixed culture; unlabeled culture or name discrepancy between specimen and test request label