Mycoplasma pneumoniae Antibodies, IgG
Also known as: Atypical Pneumonia, PPLO Antibodies
Use
Aid in the diagnosis of atypical pneumonia, which is a cause of community-acquired pneumonia. Primary infection usually occurs in children and reinfection in adults is common. Results must be interpreted in light of each patient's history, physical examination, and other diagnostic findings.
Special Instructions
A single positive IgG result may be present in the absence of any clinical symptoms as specific IgG antibodies may remain elevated for up to one year after the initial infection. Recent or acute infection can only be documented by a positive Mycoplasma IgM result and/or a significant increase in the IgG value between sera drawn two to four weeks apart. In some individuals, Mycoplasma IgG levels decline to undetectable levels after four to six months.
Limitations
A positive result indicates prior exposure to Mycoplasma. The reference interval established is intended as a baseline only. Values >100 may indicate a recent infection with Mycoplasma pneumoniae and need to be confirmed either by a positive IgM result and/or an additional specimen drawn 2-4 weeks later showing a significant increase in antibody levels.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 5255-5
- 5255-5
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |